Figure 5
P2-mediated expression of Runx1 is required for embryonal thymopoiesis. (A) Distribution of CD44/CD25 expressing thymocytes of E15.5 WT and P2neo/neo embryos. Representative data of five different experiments are shown as FACS dot plots; percentages of cells in each quadrant are indicated. (B) Distribution of embryonic and neonatal CD4/CD8 thymocytes. WT and P2neo/neo thymocytes of E16.5 and E17.5 embryos and day 1.5 and 3.5 neonates were analyzed. Representative data of five different experiments are shown as FACS dot plots; percentages of cells in each quadrant are indicated.