Figure 3From: Extra-embryonic endoderm cells derived from ES cells induced by GATA Factors acquire the character of XEN cellsContribution of gExEn cells to ExEn lineage in vivo. (A, B) 8.5 dpc chimeric embryos derived from 5G6GR-GFP ES cells. 5G6GR-GFP ES cells, kept in undifferentiated state without Dex, give rise to embryonic chimeras. The 8.5 dpc chimeric embryos with g6ExEn-GFP (C, D) derived from 5G6GR-GFP ES cells or g4ExEn-GFP cells (E, F) derived from 5G4GR-GFP ES cells, cultured in the presence of Dex for the activation of GATA-GR after several passages, contributed only to the distal parietal yolk sac.Back to article page