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Figure 3 | BMC Developmental Biology

Figure 3

From: Extra-embryonic endoderm cells derived from ES cells induced by GATA Factors acquire the character of XEN cells

Figure 3

Contribution of gExEn cells to ExEn lineage in vivo. (A, B) 8.5 dpc chimeric embryos derived from 5G6GR-GFP ES cells. 5G6GR-GFP ES cells, kept in undifferentiated state without Dex, give rise to embryonic chimeras. The 8.5 dpc chimeric embryos with g6ExEn-GFP (C, D) derived from 5G6GR-GFP ES cells or g4ExEn-GFP cells (E, F) derived from 5G4GR-GFP ES cells, cultured in the presence of Dex for the activation of GATA-GR after several passages, contributed only to the distal parietal yolk sac.

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