(a) Alignment of predicted amino acid sequences from Talia, XE7 and homologues from other metazoans within the region of homology. The most highly conserved region, corresponding to exon 3 of Talia, is boxed. Highly conserved amino acids (in > 50% of sequences) are highlighted. Human TALIA (not shown) includes two "stop" codons at the equivalent of positions 234 and 248 in the alignment. Accession numbers of nucleotide sequences, from which protein sequences were predicted, were: Talia (Mus musculus) – AW261571; XE7 (Homo sapiens) – NM_005088; Danio rerio – NM_200682; Drosophila melanogaster – NM_169093; Caenorhabditis elegans – NM_066250.