Figure 4
From: Requirement of histone deacetylase activity for the expression of critical photoreceptor genes
Luciferase reporter analysis of Nrl and Crx promoters in P2 mouse retinal explants (n = 3). Firefly luciferase reporter constructs driven by Nrl or Crx promoter were electroporated into retinal explants. Co-electroporation of a renilla luciferase reporter construct driven by a ubiquitous CAG promoter was used to normalize differences in the transfection efficiency. TSA-treated reporter activity is expressed as a percentage of the normalized DMSO-treated reporter activity.