Protein Kinase D regulates several aspects of development in Drosophila melanogaster

Table 1 Human PKD can replace Drosophila PKD activity

UAS-Line	n	0/1	2	3
GFP-lacZ	19	0%	0%	100%
PKD-WT^10-2	44	77,2%	4,6%	18,2%
PKD-SE^139-2	35	94,3%	2,9%	2,8%
hPKD2^II-3	22	63,6%	36,4%	0%
hPKD2^X-2	16	89,0%	8,3%	2,7%
hPKD3^V-1	28	79,6%	14,3%	6,1%
hPKD3^X-1	21	86,5%	8,1%	5,4%
PKCi	23	0%	0%	100%

The given UAS-line was overexpressed along the antero-posterior border with help of the ptc-Gal4 driver line together with UAS-dsPKD^6-4. As control, ptc > dsPKD^6-4 was crossed to UAS-GFP-lacZ and wings used for comparison. Wings of at least ten flies were mounted and examined at high magnification. n, number of wings scored. 0/1, wild type looking wing; 2, weak phenotype; 3, phenotype indistinguishable from control. Numbers represent percentage of wings with given phenotype.

ISSN: 1471-213X