Figure 5

Cdkn1c is the key regulator of embryonic growth within the IC2 imprinted domain on mouse distal chromosome 7. Summary of the reported genotypes and phenotypes associated with the imprinted genes on mouse distal chromosome 7. Black arrowheads indicate the positions of the known IC for the two domains. The number of expressed gene copies present in each genotype is shown with the top row being the normal, wild type state. The reported weight phenotypes are for maternal disomy distal chromosome 7 [22], paternal inheritance of the KvDMR1 deletion [25], maternal inheritance of an 800 kb YAC [42] and data from this paper. The strain backgrounds are C57BL/6 where indicated.