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Figure 5 | BMC Developmental Biology

Figure 5

From: Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity

Figure 5

Novel roles of specific spliceosome components in the synMuv B pathway. RSR-2, LSM-2, LSM-4 and SM proteins may have functions that reduce gene expression and are independent of pre-mRNA splicing. The phenotypic overlap with lin-35 Rb mutants may indicate functions in transcription repression, chromatin modification, miRNA/RNAi pathway modulation or mRNA metabolism.

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BMC Developmental Biology

ISSN: 1471-213X

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