Figure 1

(A, B) Color code representation of the strength of RNAi phenotypes of candidate genes in different genetic backgrounds. Red indicates a highly penetrant lethal phenotype. Yellow designates a substantially weaker phenotype and/or increase in viable progeny and white indicates weak or no detectable defects. (A) Synthetic lethal or enhanced RNAi phenotypes. (B) RNAi phenotypes enhanced in synMuv B mutants See: Additional file 1, Supplementary Table 1, for details. (C) Pie Chart representing the major functional categories among the 57 candidates genes (See Additional file 1, Supplementary Table 1C). (D) Pie Chart representing major functional categories among 14 genetic interactors previously published (See Additional file 3, Supplementary Figure 1).