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Table 1 Summary of all characterization experiments performed along with their outcome.

From: Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow

  SEQUENTIAL COCKTAIL SEQUENTIAL TSA COCKTAIL TSA
ENDOGENIC DIFFERENTIATION     
Cytological staining     
PAS ++ - NT NT
Immunofluorescence     
AFP, HNF3β, ALB, CK18, HNF1α, C/EBPα, MRP2 - - +++ ++
Functional analysis     
ALB secretion - - +++ ++
Ureogenesis - - +++ ++
EROD activity - - +++ ++
Inducible EROD activity - - +++ ++
PROD activity + - +++ ++
Inducible PROD activity - - +++ ++
  1. (-): negative; (+),(++),(+++): weak positive, positive, strong positive, respectively; NT: not tested.