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Table 1 Retinoic acid signalling components in selected postmitotic hindbrain and isthmic structures

From: Retinoic acid is a potential dorsalising signal in the late embryonic chick hindbrain

 

Roofplate

Meninges

Locus coeruleus

Isthmic midbrain

Vestibulo-acoustic nuclei

Caudal hindbrain nuclei

 

Retinoic acid pathway component

non-neural tissue

neural tissue

 

Raldh1

  

√

√1

√

 

synthesis

Raldh2

√

√

 

√2

 

√

 

Raldh3

   

√3

   

Cyp1B1

√

√

     

Crabp1

    

√

 

binding

Cyp26A1

√

  

√1

 

√

 

Cyp26B1

  

√

   

breakdown

Cyp26C1

√

  

√1

 

√

 

RAR (βγ)

ubiquitous

RXRγ

√

 

√

(√)

(√)

√

 
  1. 1isthmo-optic region, 2 proximal to the oculomotor nuclei, 3 isthmic organiser