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Table 3 Development of CA groups in lmx1b.1/2 double morphants.

From: Expression and function of nr4a2, lmx1b, and pitx3in zebrafish dopaminergic and noradrenergic neuronal development

 

MOlmx1b1/2

MOlmx1b1/2 + MOp53

 

72hpf

96hpf

72 hpf

96 hpf

vDC group1

reduced (36/36)

reduced (71/87)

reduced (10/31)

reduced (13/19)

vDC group3

normal (36/36)

normal (87/87)

normal (31/31)

normal (19/19)

posterior vDC

dispersed (32/36)

dispersed (72/87)

dispersed (31/31)

dispersed (15/19) reduced (10/19)

PO

normal (36/36)

normal (87/87)

normal (31/31)

normal (19/19)

Pr

normal (36/36)

normal (87/87)

normal (31/31)

normal (19/19)

ACL

reduced (10/36)

normal (87/87)

normal (31/31)

reduced (7/19)

OB

reduced (14/36)

reduced(24/87)

normal (31/31)

normal (19/19)

LC

n.a.

n.a.

normal (31/31)

normal (19/19)

MO

reduced (34/36)

reduced (9/49)

reduced (6/31)

normal (19/19)

HB ectopic th

yes (22/36)

yes (20/49)

yes (5/31)

yes (3/19)

  1. The numbers in brackets represent the number of morphants that show the respective phenotypes and the total number of analyzed morphants. A visual estimate indicated an increase of th expressing cells in the LC of lmx1b.1/2 morphants, but unambiguous cell counting was not possible due to dense clustering of the cells. Abbreviations are as in Table 2. HB, hindbrain.
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BMC Developmental Biology

ISSN: 1471-213X

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