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Table 2 Development of CA groups in nr4a2, nr4a2a and nr4a2b morphants.

From: Expression and function of nr4a2, lmx1b, and pitx3in zebrafish dopaminergic and noradrenergic neuronal development

     

MOnr4a2 + MOp53

 

MOnr4a2

72hpf

MOnr4a2a

72hpf

MOnr4a2b

72hpf

MOnr4a2

96hpf

72 hpf

96 hpf

vDC group1

normal (23/23)

normal (14/17)

normal (25/25)

normal (28/28)*

normal (28/28)

normal (30/30)

vDC group3

normal (23/23)

normal (17/17)

normal (25/25)

normal (28/28)

normal (28/28)

normal (30/30)

posterior vDC

normal (23/23)

normal (17/17)

normal (25/25)

normal (43/43)

normal (28/28)

normal (30/30)

PO

absent (25/26)

absent (16/17)

normal (25/25)

absent (25/43) reduced (15/43)

absent (22/28)

absent (19/30)

Pr

absent (25/26)

absent (17/17)

normal (18/25)

absent (10/43) reduced (33/43)

absent (22/28) reduced (6/28)

absent (9/30) reduced (21/30)

ACL

absent (25/26)

absent (17/17)

reduced (16/25)

absent (15/43) reduced (28/43)

absent (28/28)

absent (23/30) reduced (7/30)

OB

normal (23/23)

n.a.

normal (25/25)

normal (43/43)

normal (28/28)

normal (30/30)

LC

normal (26/26)

normal (17/17)

normal (25/25)

normal (43/43)

normal (28/28)

normal (30/30)

MO

normal (26/26)

n.a.

reduced (15/25)

normal (43/43)

normal (28/28)

normal (30/30)

  1. The numbers in brackets represent the number of morphants that show the respective phenotypes and the total number of analyzed morphants. (n.a. – not analyzed). Notes: (*) morphants with general morphological defects may sometimes form less DA cells. Abbreviations of the different CA groups: ACL, amacrine cell layer; vDC, ventral diencephalic; posterior vDC, ventral diencephalic groups from 2 and 4 to 6; LC, locus coeruleus; MO, medulla oblongata; OB, olfactory bulb; PO, preoptic area; Pr, pretectum.