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Figure 5 | BMC Developmental Biology

Figure 5

From: Incudomalleal joint formation: the roles of apoptosis, migration and downregulation

Figure 5

Inhibition of caspases has no effect on the formation of the incudomalleal joint. (A) Limb grown for 24 hours in 1% DMSO control medium. (B) Limb grown for 24 hours with Z-VAD-FMK caspase inhibitor. Arrows in (B) point to interdigit webbing in the limbs treated with inhibitor. (C) Middle ear culture grown for three days with Z-VAD-FMK. Arrow points to the incudomalleal joint. M = malleus and I = incus. Scale bar (C) = 200 μm.

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