Figure 4
From: Incudomalleal joint formation: the roles of apoptosis, migration and downregulation
Joint formation appears normal at E17.5 in Apaf-1 mutants. (A) Trichrome stained section of incudomalleal joint at E17.5 in an Apaf-1 wildtype littermate. (B) Trichrome stained section of incudomalleal joint at E17.5 in an Apaf-1 homozygote mutant. (C) Skeletal preparation with alcian blue staining of Apaf-1 wildtype littermate. (D) Skeletal preparation with alcian blue staining of Apaf-1 homozygous mutant. No defect in shaping of the articulation is observed. M = malleus. I = Incus. Scale bar in (A) = 200 μm. Scale bar in (C) = 400 μm.