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Table 3 Injection of N-cad mRNA does not correct the NTD in MZoep mutants

From: Nodal signaling is required for closure of the anterior neural tube in zebrafish

  

Pineal morphology

Embryo

Dose of N-cad mRNA (pg)

Round

Expanded

Divided

WT

0

75

0

0

WT

1.9–75

37

0

0

MZoepm134

0

0

1

29

MZoepm134

0.6–7.5

2

11

58

MZoepm134

25–75

1

1

33

  1. Embryos were fixed at approximately 1 dpf and processed for whole mount in situ hybridization with an antisense probe to otx5.