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Figure 5 | BMC Developmental Biology

Figure 5

From: Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island

Figure 5

(A-B) Whole mount view of the lungs of the double transgenic and the control littermate showing the enlargement of the airspaces, which are highlighted in B (top is the non-Tg and lower is the Tg lung). (C) Lateral views of a double transgenic hnRNPA2B1-rtTA2S-M2 line 9/TRE-myc-GATA-6 (Tg) and a control litter mate (non-Tg) at gestational age 12.5 dpc 24 hours after start of induction with Dox. The arrow indicates the clearly visible oedema after induction of the GATA-6 transgene. (D) Ventral (top) and dorsal (bottom) views of the double transgenic hnRNPA2B1-rtTA2S-M2 line 9/TRE-myc-GATA-6 to show the clear indication of oedema (arrows).

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