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Table 1 Homology comparison among Dab2 and Dabl from different species

From: XenopusDab2 is required for embryonic angiogenesis

Identity Percentage

  

Dab2

Dab1

  

Xenopus

Zebrafish

Mouse p96

Mouse p67

Ratp82

Rat p59

Human

Zebrafish

Mouse

Rat

Human

Dab2

Xenopus

100

47.6

41.6

57.6

41.4

57.3

44.5

35

35.5

35.5

35.9

 

Zebrafish

-

100

33.5

45.2

33.9

45.5

34.2

33.3

33.4

33.3

32.9

 

Mouse p96

-

-

100

71.5

94.4

67.4

82.8

27.5

31.2

31.3

31.6

 

Mouse p67

-

-

-

100

67.4

94.2

57.6

32. 6

37

37.6

37

 

Ratp82

-

-

-

-

100

71.6

82.7

26.9

30.8

31.4

31.1

 

Ratp59

-

-

-

-

-

100

58.1

32.5

36.9

37.4

36

 

Human

-

-

-

-

-

-

100

28.9

31.5

32.2

32.1

Dab1

Zebrafish

-

-

-

-

-

-

-

100

62.9

63.4

63.9

 

Mouse

-

-

-

-

-

-

-

-

100

98.9

96.6

 

Rat

-

-

-

-

-

-

-

-

-

100

96.8

 

Human

-

-

-

-

-

-

-

-

-

-

100

  1. XDab2 amino acid sequence is more homologous to other vertebrate Dab2 than to Dab1 and is most similar to short splicing isoforms of mammalian Dab2 (mouse p67, 57.6% identity; rat p59, 57.3% identity) as shown here.
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BMC Developmental Biology

ISSN: 1471-213X

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