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Table 1 Effect of Gabexate mesylate on pregnancy.

From: Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation

Group # mice # pregnant # embryos Rate (%)
Control 1 6 6 72 100
Gabexate 1 11 1 2 2.8
Control 2 4 4 22 100
Gabexate 2 6 1 3 13.6
  1. Uterine horns of 2.5 dpc pregnant dams were injected with 10 ul each of saline (control) or the Gabexate mesylate (10 mM). Animals were sacrificed and examined for pregnancies at 7.5 dpc. % Rate of pregnancy was calculated by assuming the rate of pregnancy in Controls as 100%.