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Figure 5 | BMC Developmental Biology

Figure 5

From: Zona pellucida from fertilised human oocytes induces a voltage-dependent calcium influx and the acrosome reaction in spermatozoa, but cannot be penetrated by sperm

Figure 5

Effects of pimozide on the Ca2+ influx stimulated by hZP. Spermatozoa were capacitated in the presence or absence of 10 μM pimozide. They were then loaded with Fura-2 in BWW medium and hZP (2/μl) was added (n = 3 experiments). The results are expressed as the mean ± SEM of Ca2+ influx induced by hZP, for the peak and the sustained phase; *p < 0.001, Mann and Whitney test.

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