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Figure 4 | BMC Developmental Biology

Figure 4

From: Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

Figure 4

Normal cardiac NCC migration in Alk5/Wnt1-Cre mutants. The OFT of controls (A, C, E) and Alk5/Wnt1-Cre mutants (B, D, F) display similar staining patterns when analyzed using the R26R lineage tracing assay at E11.0. A-B, whole mount staining (left lateral image); C-F, transverse sections on the level of the 4th (C, D) and 6th (E, F) PAAs. Arrows (A-F) point to the most proximal location staining positive for the β-galactosidase activity.

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