From: Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6
Genotype
Eyes n =
Cornea-lens
Cornea-iris
Iris-lens
Retina-lens
Iris-retina
Wt
17
0%
Gli3 +/-
25
28%
Pax6 +/-
16
38%
Pax6 +/- ; Gli3 +/-
28
36%
64%
68%
39%
7%