Retinal morphology of wild-type (A), Gli3+/- (B, E), Pax6+/- (C) and Pax6+/-;Gli3+/- (D, F-H) animals. Although a majority of Gli3+/- retinae exhibit normal lamination (B), mild focal dysplasia is seen (E). Pax6+/-; Gli3+/- retinal phenotypes include thinning of the retina (D) and dysplasia (F-H). gcl, ganglion cell layer; inl, inner nuclear layer; onl, outer nuclear layer; ipl, inner plexiform layer; opl, outer plexiform layer; r, rosette. Scale bars = 100 μm.