Figure 11

Immunolocalization of RelB and NFκB2 in mCMV-infected E15 + 6 SMGs. A-C. RelB localization. Insert: NFκB2 localization. In control SMGs, RelB (A) (black arrowheads) and NFκB2 (insert, white arrows) are seen in epithelia surrounding forming lumina and not in the stroma. With CMV infection (B, C), RelB is seen in the nuclei of stromal cells (black arrows), many of which exhibit inclusion bodies. RelB is also seen in the nuclei of ductal epithelia (black arrowheads) surrounding enlarged lumina (C). In CMV-infected glands, NFκB2 is seen in the cytoplasm of large stroma cells (insert, white arrowheads) and epithelia surrounding lumina (data not shown). Bar: 50 μm.