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Figure 1 | BMC Developmental Biology

Figure 1

From: Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophiladevelopment

Figure 1

Mammalian and Drosophila ROCK proteins. (A) Schematic representation of several major ROCK substrates and the functions they mediate either in mammalian cells or in Drosophila tissues. (D)MBS: (Drosophila) Myosin Binding Subunit of Myosin Phosphatase; MLC: Myosin Light Chain; MHC: Myosin Heavy Chain; LIMK: LIM kinase; Sqh: Drosophila non-muscle Myosin Light Chain; Zipper: Drosophila non-muscle Myosin Heavy Chain. (B) The structure of mammalian and Drosophila ROCK proteins. The N-terminal kinase region of DRok, Drok-cat (amino acid 1 to 530) was isolated to express a contitutively active form of DRok. RBD: Rho-Binding Domain; PH: Plekstrin-Homology domain; CRD: Cysteine-Rich Domain.

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BMC Developmental Biology

ISSN: 1471-213X

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