Lens fate is lost in the central ocular ectoderm of β-catenin gain-of-function mice. Cryosections of the indicated embryonic age and genotype showing Sox2 (A-D), Prox1 (E-H), Hes1 (I, J) and β-tubulin (K-P) immunolabeling (red). Labeling for F-actin is also shown (green) with Hoechst 33258 nuclear labeling (blue). Arrowhead indicates processes extending from presumptive retina of Lens-cre; Catnblox(ex3) mutant mice that are positive for β-tubulin immunolabeling. Labeling abbreviations as in Fig. 1.