nfi-1 affects behavior and life-span in C. elegansbut is not essential for DNA replication or survival

Table 1 Rescue of pharyngeal pumping defect by nfi-1 transgene

Day^a	N2	nfi-1	N2 qaEx507^b	nfi-1 qaEx507 ^b
1 (n = 10)	241 ± 5	228 ± 9^c	243 ± 5	241 ± 8^e
2 (n = 12)	242 ± 10	187 ± 64^d	237 ± 8	195 ± 78^d
3 (n = 12)	214 ± 18	125 ± 79^c	183 ± 78	200 ± 72
4 (n = 12)	160 ± 62	92.5 ± 86^d	183 ± 79	133 ± 90

^a Pharyngeal pumping was counted for one minute starting on day one, when animals first reached adulthood, for four consecutive days.
^b N2 and nfi-1 mutant worms were transformed with a transgene containing the nfi-1 gene and upstream promoter and rol-6 (qaEx507).
^c This value is statistically significantly different from N2 (P < 0.01)
^d This value is statistically significantly different from N2 (P < 0.05)
^e This value is statistically significantly different from nfi-1 (P < 0.01)

ISSN: 1471-213X