Figure 7

Airway reactivity in AdCMVAScftr-treated rats. Fetuses at 16 days gestation were treated with either AdCMVlacZ (black; n = 5) or AdCMVAScftr (red; n = 5). Animals were maintained in filtered cages to minimize exposure to environmental pathogens. At 6–12 months of age, changes in airway resistance (Raw) were determined in response to nebulized saline and acetylmethylcholine at concentrations of 3.125, 12.5, and 50 mg/ml.