Figure 3

Airway fibrosis following in utero AdCMVAScftr therapy. Lung sections were stained with Masson's Trichrome to visualize collagen (blue) in 100 day old rats. There was increased collagen in both the small (Panel C) and large airways (Panel D) of the AdCMVAScftr-treated rats when compared to control airways of the same size (Panels A and B). The morphometric quantitation of this fibrosis (Table 1) confirmed that these changes were consistent throughout the lung fields examined. Original magnifications 100×.