Figure 2
From: Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice
Normal germ cell development in the absence of Dppa3 . A, Gonads from E12.5 embryos (above: wild type; below: Dppa3tm1WHT/Dppa3tm1WHT) stained for alkaline phosphatase to reveal primordial germ cells. B, RT-PCR analysis of gene expression in wild-type and Dppa3tm1WHT/Dppa3tm1WHTadult ovaries. C,D, Dppa3tm1WHT/Dppa3tm1WHTtestis (C) and ovary (D) are histologically normal.