Regulation of signaling genes by TGFβ during entry into dauer diapause in C. elegans

Table 2 Comparison of microarray data to published experiments.

Gene	Method	Published difference	Fold change, this study	P value
C27H5.5/col-36	RT-PCR	L2d/dauer >> L2/L3^a [64]	6.8	<0.008
C47G2.1/cut-1	Northern	L2d/dauer >> L2/L3^a [65]	5.7	<0.003
C08A9.1/sod-3	Northern	present in dauer, absent in non-dauer [66]	7.8	<0.00001
T01B7.7/rol-6	Northern and slotblot	L2/L3 >> L2d/dauer^a [61]	-7.4	<0.00002
B0491.2/sqt-1	Northern and slotblot	L2/L3 >> L2d/dauer^a [61]	-7.0	<0.0002
T23G5.1/rnr-1	GFP fusion	not seen at L2d/dauer molt, seen in cells in S phase at L2/L3 molt [67]	-1.8	<0.05^a
W01B6.7/col-2	Northern and slotblot	L2d/dauer >> L2/L3^a [61]	2.2	<0.02
T13B5.4/col-40	RT-PCR	L2d/dauer >> L2/L3^a [64]	1.1	<0.8

^a L2d/dauer refers to animals near the molt between these two larval stages; L2/L3 also refers to animals near the molt.
^b The P value for rnr-1 was calculated using only the local standard deviation because the global standard deviation was not available.

ISSN: 1471-213X