Table 3 IGF-/PTEN/Akt and Ras/Raf/MAP pathway A subset of genes related to Igf/PTEN pathway that are expressed in undifferentiated ES cells is shown. Note that the overall pattern of expression suggest that this pathway is active in undifferentiated ES cells.
Tpm ES | Tpm EB | Unigene ID | Locus ID | Description |
|---|---|---|---|---|
14 | 32 | Hs.239176 | 3480 | IGF-1 receptor |
N.D. | N.D. | Hs.390242 | 3667 | IRS-1 |
0 | 0 | Hs.253309 | 5728 | PTEN |
N.D. | N.D. | Hs.32942 | 5294 | PI3K |
11 | 8 | Hs.433611 | 5163 | PDK1 |
0 | 15 | Hs.92261 | 5164 | PDK2 |
N.D. | N.D. | Hs.6196 | 3611 | ILK |
75 | 157 | Hs.368861 | 207 | AKT1 |
15 | 82 | Hs.170133 | 2308 | FKHR (FoxO1A) |
78 | 54 | Hs.14845 | 2309 | FKHRL1 (FoxO3A) |
15 | 88 | Hs.282359 | 2932 | GSK3beta |
39 | 14 | Hs.238990 | 1027 | p27 |
280 | 240 | Hs.371468 | 595 | Cyclin D1 |
0 | 594 | Hs.370771 | 1026 | p21 |
1 | 10 | Hs.329502 | 842 | Caspase 9 |
0 | 39 | Hs.76366 | 572 | Bad |
98 | 193 | Hs.260523 | 4893 | N-Ras |
2 | 0 | Hs.37003 | 3265 | H-Ras |
35 | 128 | Hs.257266 | 5894 | Raf1 |
N.D. | N.D. | Hs.132311 | 5604 | MEK1 |
128 | 218 | Hs.366546 | 5606 | MEK2 |
37 | 75 | Hs.324473 | 5594 | ERK (p42 MAPK) |