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Figure 5 | BMC Developmental Biology

Figure 5

From: Expression of the Hsp23 chaperone during Drosophila embryogenesis: association to distinct neural and glial lineages

Figure 5

Regulation of hsp23 developmental expression. (A) Neuroectodermal expression of Hsp23 is maintained in a stage 11 single-minded mutant. (A' and A") Confocal High magnification views of region in brackets in A displaying co-expression of Hsp23 (red, A') and 22C10 (green, A") in cells of the MP2 lineage. (B) Detection of hsp23 mRNA in additional MP2 neuroblasts generated in a delta mutant. Graph: Modulation of the proximal hsp23 promoter by the Single-minded (Sim), Tango (Tgo) and Drifter (Drf) transcription factors. Normalized β-Galactosidase activity obtained after transfection in S2 cells is shown. Note the capacity of Sim and Tgo to activate hsp23 promoter and the potent repressive effects of Drf.

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