Figure 7From: Mesenchymally-derived Insulin-like growth factor 1 provides a paracrine stimulus for trophoblast migrationImmunofluorescence of first trimester anchoring villi showing reactivity for (a) IGFR-1, (b) insulin receptor, and (c) IRS-1. Staining is prominent in cytotrophoblast columns that occupy the lower part of the field in each case, and is also seen in (a) and (b) in some mesenchymal cells above the column. (d) IRS-2 is negative in a similar field.Back to article page