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Figure 1 | BMC Developmental Biology

Figure 1

From: Mesenchymally-derived Insulin-like growth factor 1 provides a paracrine stimulus for trophoblast migration

Figure 1

First trimester villous explants cultured on a collagen gel support in (a) IGF-II (6 days) or (b) activin AA (6 days) showing stimulation of cytotrophoblast migration across the gel surface. Note the separated bipolar cells oriented in the direction of migration. In (c) is shown an explant cultured for 7 days in the presence of TGF-β1. Cells are mainly rounded and migration is very limited.

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BMC Developmental Biology

ISSN: 1471-213X

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