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Figure 6 | BMC Developmental Biology

Figure 6

From: Chitosan/siRNA nanoparticle targeting demonstrates a requirement for single-minded during larval and pupal olfactory system development of the vector mosquito Aedes aegypti

Figure 6

Expression and knockdown of sim in pupae. sim is expressed in the antennal lobe (A, B) and antenna (A1, B1) of wildtype (A, A1) and control-fed (B, B1) 36 hr APF pupae. Cell clusters of sim expression surrounding the antennal lobe (A, B) are highlighted by red dots, while clusters of sim expression are marked by red arrowheads in the antenna (A1, B1). Animals fed with knockdown (KD) siRNAs sim430(C, C1) and sim718(D, D1) lack sim expression in the antennal lobe region (C, D) and antenna (C1, D1). Antennal lobes are denoted by yellow-dotted circles. Dorsal is oriented upward in panels A-D. The proximal ends of antennae are oriented upward in A1-D1. Scale bars = 25 microns.

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