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Figure 2 | BMC Developmental Biology

Figure 2

From: Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice

Figure 2

Skull morphology of Fgfr2+/P253Rand Fgfr2+/S252WApert syndrome mice and unaffected littermates at E17.5 and P0. Left lateral views of 3D HRμCT reconstructions of representative mice from our study samples: Fgfr2+/P253R mutant at E17.5 (A) and P0 (B): unaffected littermate of the P253R model at E17.5 (C) and P0 (D); Fgfr2+/S252W mutant at E17.5 (E) and P0 (F); unaffected littermate of the S252W model at E17.5 (G) and P0 (H). By P0, midfacial retrusion is more severe and fusion of multiple sutures is apparent.

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