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Figure 2 | BMC Developmental Biology

Figure 2

From: Metabolomic insights into system-wide coordination of vertebrate metamorphosis

Figure 2

Distinct metabolite abundance patterns that were consistently observed in the datasets. After inspecting the abundance patterns of individual metabolites, a total of 13 different expression patterns were observed in the datasets consistently. The frequency of the observed patterns is tabulated in Table 3. (A) Monotonic ↑. (B) Monotonic ↓. (C) ↑ at the froglet stage (TK > XXV). (D) ↓ at the froglet stage (TK > XXV). (E) ↓ after the premetamorphic stage (TK VI–X). (F) ↑after the premetamorphic stage (TK VI–X). (G) ↑ at the metamorphic climax (TK XXI–XXII) then return to a basal level. (H) ↓ at the metamorphic climax (TK XXI–XXII) then return to a basal level. (I) ↑ at the metamorphic climax (TK XXI–XXII) followed by ↓ at the froglet stage (TK > XXV). (J) ↓ at the metamorphic climax (TK XXI–XXII) followed by ↑ at the froglet stage (TK > XXV). (K) Significant abundance change at the metamorphic climax, and the abundance remains constant at the froglet stage. (L) Step-wise ↑ or ↓. (M) Significant variation (significant unequal variance determined by the Levene’s test, padj < 0.01).

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