Figure 10

Significant abundance changes of the metabolites in the sphingolipid metabolism pathway. Glucosylceramide (GlcCer) and galactosylceramide (GalCer) are structural isomers and hence cannot be differentiated, but both metabolites are converted to distinct metabolites, so they are depicted separately. The divided circles indicate variants of that metabolite (different chain length) were detected. Abbreviations: GalCer: galactosylceramide, GlcCer: glucosylceramide, LacCer: lactosylceramide, SM: sphingomyelin. (A) Overall abundance changes of the metabolites. (B) Progression of the abundance change of the metabolites relative to the premetamorphic stage (TK VI–X). Refer to Figure 4 legend for details.