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Table 5 Number of highly regulated Xenopus proteins up regulated and down regulated at each time point after amputation and U/D ratios (bold)

From: Proteomic analysis of fibroblastema formation in regenerating hind limbs of Xenopus laevis froglets and comparison to axolotl

  11 dpa 5dpa 7 dpa 12 dpa
  U D U/D U D U/D U D U/D U D U/D
Signaling 39 44 0.9 58 38 1.5 52 34 1.5 60 35 1.7
Transport 30 30 1.0 31 36 0.9 36 32 1.1 35 35 1.0
Transcription 38 47 1.2 52 44 1.2 54 39 1.4 57 43 1.3
 CA 9 12 0.8 14 8 1.8 14 8 1.8 15 9 1.7
 TFs 18 14 1.3 17 22 0.8 18 18 1.0 20 18 1.1
 RP 11 21 0.5 21 14 1.5 22 13 1.7 22 16 1.4
Translation 22 43 0.5 48 22 2.2 57 17 3.4 59 15 3.9
 RPs 16 30 0.5 33 16 2.1 40 12 3.3 42 10 4.2
 TLFs 6 13 0.5 15 6 2.5 17 5 3.4 17 5 3.4
Cytoskeleton 34 43 0.8 45 50 0.9 48 49 1.0 60 43 1.4
 MPs 6 14 0.4 5 23 0.2 4 23 0.2 4 23 0.2
 NMPs 28 29 1.0 40 27 1.5 44 26 1.7 56 20 2.8
 ECM 24 12 2.0 30 7 4.3 28 8 3.5 28 11 2.5
Metabolism 39 53 1.4 48 76 1.7 45 76 0.6 59 74 0.8
 CM 27 37 0.7 18 45 0.4 20 45 0.4 27 43 0.6
 NCM 12 16 0.5 30 31 1.0 25 31 0.8 32 31 1.0
Protection 41 29 1.4 41 26 1.6 46 26 1.8 57 24 2.4
 INF 23 10 2.3 18 13 1.4 18 14 1.3 25 12 2.1
 APO 7 4 1.8 5 5 1.0 5 6 0.8 5 6 0.8
 CHA 11 15 0.7 18 8 2.3 23 6 3.8 27 6 4.5
Degradation 28 28 1.0 30 26 1.2 32 25 1.3 39 24 1.6
 PRO 11 15 0.7 9 13 0.7 15 13 1.2 17 11 1.5
 NPRO 17 13 1.3 21 13 1.6 17 12 1.4 21 13 1.6
Cell cycle 20 25 0.8 21 27 0.8 27 23 1.2 37 17 2.2
 G1/S 6 8 0.8 5 8 0.6 7 7 1.0 8 6 1.3
 M 4 8 0.5 8 10 0.8 8 9 0.9 13 5 2.6
 Other 10 9 1.1 8 9 0.9 12 7 1.7 16 6 2.7
  1. CA = chromatin associated; TFs = transcription factors; RP = RNA processing; RPs = ribosomal proteins; TLFs = translation factors; MPs = muscle proteins; NMPs = non-muscle proteins; CM = carbohydrate metabolism; NCM = non-carbohydrate metabolism; INF = inflammation; APO = apoptosis related; CHA = chaperones; PRO = proteasome associated; NPRO = non-proteasome associated.