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Figure 3 | BMC Developmental Biology

Figure 3

From: Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line

Figure 3

CLIC4 is expressed in neuroprogenitor cells in the subgranular zone (SGZ) of the hippocampal dentate gyrus. (A) Image downloaded from Allen Mouse Brain Atlas [48] showing cells expressing Clic4 transcripts in the SGZ (arrows). (B) Double immunofluorescence for CLIC4-GFP (green) and doublecortin (DCX, red) in the adult mouse dentate gyrus; cell nuclei are labeled by DAPI (blue). (C, D) Most of the SGZ cells are positive for CLIC4-GFP and, a subset of these neuroprogenitor cells (arrows) co-express DCX. Samples of GFP-positive neuroprogenitor cells not expressing DCX, which are likely to represent early progenitors, are marked with arrowheads.

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