Skip to main content
Figure 4 | BMC Developmental Biology

Figure 4

From: Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6

Figure 4

Regulation of lin-39 levels by transcription factors in vivo (qRT-PCR) . A) Decrease in lin-39 transcript levels in nhr-43, lin-26, tbx-9, bed-3 mutant and ztf-17(RNAi) animals. B) Decrease in lin-39 transcript levels when activity of both elt-6 and egl-18 is reduced. C) Increase in lin-39 transcript levels when either elt-6 or egl-18 was overexpressed from the heat shock promoter. All analyses were done on L3 stage animals. The mean values for each genotype were obtained from at least two independent experiments and normalized to the housekeeping gene, gpd-2, as internal standard. The data was analyzed with unpaired t-test compared to the appropriate control. ‘*’ indicates P-value < 0.05.

Back to article page