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Table 1 Tenm4 m1/m1 mutant embryo BrdU incorporation and TUNEL assay results

From: Mouse Tenm4 is required for mesoderm induction

i) BrdU (E6.5)

wt or m1/+ (n=24)

m1/m1 (n=13)

Total cells (per section)

88.2 (±11.5)

62.2 (±4.66)

BrdU labeled cells

42.1 (±6.41)

29.2 (±3.67)

Labeling index (%)

47.7 (±4.45)

46.9 (±2.59)

ii) TUNEL assay (E7.5)

wt or m1/+ (n=10)

m1/m1 (n=6)

Embryonic region

1.2 (±0.44)

0.17 (±0.41)

Extraembryonic region

11.3 (±3.11)

0.50 (±0.84)

  1. i) BrdU incorporation at E6.5. ii) TUNEL assay at E7.5. Numbers in parentheses are standard deviation (±SD).
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BMC Developmental Biology

ISSN: 1471-213X

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