Figure 11
From: The role of Zic transcription factors in regulating hindbrain retinoic acid signaling
Knockdown of Aldh1a2 causes a reduction in the vagal neuron domain. Analysis of vagal motor neurons in Tg(isl1:eGFP) transgenic embryos injected with either a p53 control morpholino (1 ng, A) or an Aldh1a2 morpholino (2 ng, B). The length of the vagal domain was quantified using Image J (C). Significance calculated using an unpaired t-test (*p-value ≤0.01; n = 2, 6 for quantification of p53MO and Aldh1a2 MO, respectively).