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Figure 5 | BMC Developmental Biology

Figure 5

From: The Ecdysone receptor constrains wingless expression to pattern cell cycle across the Drosophilawing margin in a cyclin B-dependent manner

Figure 5

Overexpression of CycB or knockdown of Wg partially restores cell cycle patterning in EcR RNAi clones. (A-D) - UAS-CycB clones (marked with CD8-RFP in A) do not disrupt PCNA-GFP patterning across the anterior margin (B). The merge is shown in (C) and overlap with DNA in D. (E-H) - Overexpression of CycB partially restores PCNA-GFP patterning (F, see arrow for remaining G1 cells) in EcR RNAi clones marked with CD8-RFP in (E). The merge is shown in (G) and overlap with DNA in (H). (I-L)- wg RNAi clones marked with CD8-RFP (I) disrupt CycB-PT patterning (J, see arrow). The merge is shown in (K) and overlap with DNA in (L). (M-P) - The double wg RNAi and EcR RNAi clones marked with CD8-RFP (M) result in restoration of CycB-PT patterning (N). The merge is shown in (O) and overlap with DNA in (P).

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