Table 2 Expression profiles of PRL family genes in embryos, larvae, and adult normal tissues
Species | Gene | Embryonic and/or larval expression domains | Expression in adult tissue |
|---|---|---|---|
Rat | PRL-1 | Brain [13] | In brain, skeletal muscle, and digestive epithelial tissues [1, 13–15] |
PRL-2 | ND | Ubiquitous expression [16] | |
PRL-3 | Fetal heart [17] | ND | |
Mouse | PRL-1 | Most tissues except heart and skeletal muscle [18] | ND |
PRL-2 | ND | Preferential in skeletal muscle [3] | |
PRL-3 | ND | Preferential in heart and skeletal muscle; also in small intestine [3, 21] | |
Human | PRL-1 | ND | Ubiquitous expression except brain cortex [19] |
PRL-2 | ND | Ubiquitous expression [19] | |
PRL-3 | ND | Mainly in heart and skeletal muscle; pre-erythrocytes in bone marrow [17, 20] | |
Zebrafish | PRL-1 | Mainly in neuronal cell lineage | ND |
PRL-2 | Mainly in neuronal cell lineage | ND | |
PRL-3 | Mainly in skeletal muscle | ND | |
Amphioxus | PRL | Ubiquitous in embryos; Central nervous system in larvae | ND |
Drosophila | PRL | Developing mid-gut and central nervous system in embryos; Imaginal discs in larvae | ND |