Table 1 Microarray expression profiling of SHH signaling in human tooth germ at the cap stage

SHH

sonic hedgehog

AI192528

7.291(0.011) *

8.610(0.044) *

4.671(0.032) *

PTCH1

patched 1

BG054916

3.356(0.003) **

3.380(0.002) **

4.249(0.002) **

PTCH2

patched 2

NM_003738

0.805(0.975)

1.522(0.422)

1.015(0.368)

SMO

Smoothened

NM_005631

1.052(0.010) **

1.586(0.317)

1.156(0.160)

GLI1

GLI family zinc finger 1

NM_005269

1.537(0.009) **

1.701(0.028) *

2.426(0.030) *

GLI2

GLI family zinc finger 2

NM_030379

1.135(0.042) *

1.258(0.193)

1.262(0.098)

GLI3

GLI family zinc finger 3

AW021102

1.854(0.001) **

1.580(0.083)

1.607(0.039) *

GAS1

growth arrest-specific 1

AI161237

0.635(0.007) **

0.640(0.784)

0.507(0.480)

HHIP

hedgehog interacting protein

AK098525

3.852(0.021) *

4.297(0.019) *

2.666(0.011) *

SUFU

suppressor of fused

AF144231

1.315(0.224)

2.628(0.131)

2.027(0.051)

STK36

serine/threonine kinase 36

AU149216

1.858(0.001) **

1.762(0.073)

1.531(0.039) *