Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst

Table 1 GO terms enriched for genes upregulated in the ICM as compared to TE ^a

GO term	Count	Percent	P value	FDR^b
Biological Process
Regulation of transcription, DNA-dependent	25	6.7	0.04	43.9
Regulation of RNA metabolic process	25	6.7	0.04	49.9
Neurological system process	12	3.2	0.01	16.9
Regulation of cell proliferation	12	3.2	0.02	24.9
Immune response	12	3.2	0.03	35.4
Positive regulation of macromolecule metabolic process	12	3.2	0.03	43.1
Cognition	11	2.9	0.00	2.4
Regulation of transcription from RNA polymerase II promoter	11	2.9	0.02	29.6
Response to organic substance	10	2.7	0.01	16.8
Negative regulation of macromolecule metabolic process	10	2.7	0.04	43.9
Cell Component
Plasma membrane	34	9.1	0.02	20.7
Extracellular region	30	8.0	0.00	4.2
Extracellular region part	19	5.1	0.00	1.9
Extracellular space	12	3.2	0.02	16.9
Molecular Function
DNA binding	29	7.8	0.05	46.9
Transcription regulator activity	22	5.9	0.04	40.5
Calcium ion binding	18	4.8	0.03	32.1
Transcription factor activity	17	4.6	0.02	19.4
Enzyme binding	10	2.7	0.01	7.7

^a Only those GO terms which contained at least 10 differentially expressed genes are listed.
^b False discovery rate (x 100).

ISSN: 1471-213X