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Table 3 Organization of pericentric heterochromatin in early and late 2-cell embryos

From: 3D-FISH analysis of embryonic nuclei in mouse highlights several abrupt changes of nuclear organization during preimplantation development

 

No. of NPBs

No. of NPBs not associated with pericentromeric signals

No. of NPBs associated with pericentromeric rims

No. of NPBs associated with condensed pericentromeric patches

No. of “free” cytoplasmic pericentromeric patches

early 2-cell (n = 20)

13.75 ± 3.78

4.95 ± 1.76 (37%) b

8.10 ± 3.26 (58%) a

0.7 ± 0.57 (5%) a

2.7 ± 1.7 b

late 2-cell (n = 19)

11.78 ± 3.47

3.47 ± 1.54 (29.6%) b’

2.67 ± 1.64 (24.16%) a’

4.83 ± 2.4 (37.6%) a’

4.05 ± 2 b’

  1. Values with superscripts a and a’ are significantly different at p < 0.0001.
  2. Values with superscripts b and b’ differ at p = 0.02.