Table 5 Functional classification of Hoxa1 interactors
From: Protein interactions of the transcription factor Hoxa1
Function | Interactor | Function | Interactor |
|---|---|---|---|
Cell shape and migration | Â | Signal transduction (continued) | |
Focal adhesion associated | LIMS1 (PINCH1) | Other | MDFI |
| Â | LPXN | Â | PDLMI7 (LMP-1) |
| Â | MGAT5B | Â | PLZF |
| Â | PDCD6IP (Alix) | Â | SMOC1 |
| Â | TRIP6 | Â | Â |
Cytoskeleton binding | FHL5 (ACT) | Vesicular trafficking | PDCD6IP |
| Â | LPXN | Â | Rab33A |
| Â | PDCD6IP (Alix) | Â | SPRY2 |
| Â | TRIP6 | Â | TRAPPC6A |
Cell junctions dynamics | LNX-2 | Â | TRIM23 (ARD1) |
Signal transduction | Â | Transcription regulation | FHL5 (ACT) |
| Â | Â | Â | GRN precursor |
BMP/TGFb | PDLIM7 (LMP-1) | Â | HOXA1 |
| Â | RBPMS (Hermes) | Â | HOXD3 |
Growth factors/RTK | LIMS1 (PINCH1) | Â | HSFY1 |
| Â | PDCD6IP (Alix) | Â | IKZF2 (Helios) |
| Â | PLSCR1 | Â | LPXN |
| Â | SPRY2 | Â | MDFI (I-mfa) |
| Â | SPRY1 | Â | N4BP2L2 |
TNFR family | PDCD6IP (Alix) | Â | OGT |
| Â | RBCK1 | Â | PITX2 |
| Â | TRAF1 | Â | PLSCR |
| Â | TRAF2 | Â | PRDM14 |
| Â | TRIM23 (ARD1) | Â | RBCK1 |
| Â | TRIP6 | Â | TRAPPC6A |
Wnt/b-catenin | MDFI | Â | TRIP6 |
Focal adhesion/integrin | LIMS1 (PINCH1) | Â | ZBTB16 (PLZF) |
| Â | LPXN | Â | ZBTB32 (FAZF) |
| Â | PDCD6IP (Alix) | Â | ZZZ3 |
| Â | TRIP6 | Â | Â |
Notch | LNX-2 | Secreted protein/ECM | EFEMP2 |
Protein kinases | LGALS13 | Â | GRN |
| Â | MDFI | Â | PDCD6IP |
| Â | PLSCR1 | Â | SMOC1 |
| Â | RBCK1 | Â | Â |
| Â | RGS20 | Miscellaneous | KRT81 |
| Â | SPRY2 | Â | KRTAP |
| Â | TRIP6 | Â | PLSCR |
GPCR | RGS20 | Â | PLZF |
| Â | ZBTB16 (PLZF) | Â | RAB33A |
| Â | Â | Â | RBPMS |