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Figure 5 | BMC Developmental Biology

Figure 5

From: Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1expression in mouse limb buds

Figure 5

Dorsal and ventral restriction of GRS1 -mediated ß-galactosidase activity. (A) Grem1 transcript remains restricted to the dorsal and ventral forelimb bud mesenchyme in wild-type embryos throughout limb bud development. (B) GRS1-mediated expression of ßglob-LacZ is able to correctly restrict ß-galactosidase activity along the dorso-ventral limb bud axis. D: dorsal; V: ventral.

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BMC Developmental Biology

ISSN: 1471-213X

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